Citation:
D. Kim, C. Bowman, J. D. T. Bonis-O’Donnell, A. Matzavinos, and D. Stein, “Giant acceleration of DNA diffusion in an array of entropic barriers,” Physical Review Letters, vol. 118, no. 4, 2017.
Abstract:
We investigate with experiments and computer simulations the nonequilibrium dynamics of DNA polymers crossing arrays of entropic barriers in nanofluidic devices in a pressure-driven flow. With increasing driving pressure, the effective diffusivity of DNA rises and then peaks at a value that is many times higher than the equilibrium diffusivity. This is an entropic manifestation of “giant acceleration of diffusion.” The phenomenon is sensitive to the effective energy landscape; thus, it offers a unique probe of entropic barriers in a system driven away from equilibrium.
Full Text
DOI
BibTeX
@article{kim2017a,
author = {Daniel Kim and Clark Bowman and Jackson T. Del Bonis-O'Donnell and Anastasios Matzavinos and Derek Stein},
doi = {10.1103/physrevlett.118.048002},
journal = {{Phys. Rev. Lett.}},
month = {jan},
number = {4},
publisher = {American Physical Society ({APS})},
title = {Giant Acceleration of {DNA} Diffusion in an Array of Entropic Barriers},
url = {https://cse-lab.seas.harvard.edu/files/cse-lab/files/kim2017a.pdf},
volume = {118},
year = {2017}
}